Determination of the most physiological anaesthetic drugs and the optimum mode of administration to obtain the greatest effect of organ protection and the least postoperative side effects.

To identify factors associated with increased mortality in patients undergoing major non-heart surgery.

Detection of plasma molecular factors that act locally and remotely in remote pre and post conditioning for  ischaemia reperfusion during surgery. 

Description of the pharmacokinetics of various antibiotics in critical patients with impaired renal function.

Consolidation of new haemotherapy strategies in the perioperative period.